Inspire Pharmaceuticals Inc: Ownership

Ownership Information
Shares Outstanding 82.00 Mil
Institutional Ownership (%)64.09
Top 10 Institutions (%)40.10
Mutual Fund Ownership (%)2.09
5%/Insider Ownership (%)24.71
Float (%)75.29
Ownership Activity
Description# of HoldersShares
Total Positions 12452,556,988
New Positions350
Soldout Positions220
Net Position Change4714,214,220
Buyers8922,477,714
Sellers42-8,263,494
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Institution Name Shs Held Shs Chg %Chg $Chg* %Out %Port Rpt Date
Wellington Management Company, LLP 6,526,235 3,440,100 111.5 16,908,036 7.9 0.0 09-30-09
Deerfield Management 5,521,011 0 0.0 -1,877,144 6.7 3.8 09-30-09
BlackRock Institutional Trust Company, N.A. 3,948,417 895,295 29.3 3,635,379 4.8 0.0 09-30-09
Baker Brothers Advisors, L.L.C. 3,608,190 1,800,000 99.5 8,781,216 4.4 1.5 09-30-09
Kingdon Capital Management, L.L.C. 3,000,000 0 0.0 -1,020,000 3.6 0.7 09-30-09
Tocqueville Asset Management LP 2,923,132 2,610,132 833.9 14,501,829 3.6 0.3 12-31-09
Vanguard Group, Inc. 2,486,154 646,725 35.2 2,750,499 3.0 0.0 09-30-09
Jennison Associates LLC 1,900,000 1,900,000 100.0 9,918,000 2.3 0.0 09-30-09
Great Point Partners, LLC 1,500,000 1,500,000 100.0 7,830,000 1.8 6.1 09-30-09
Schroder Investment Management Ltd. (SIM) 1,449,283 1,449,283 100.0 7,565,257 1.8 0.1 09-30-09
TCW Asset Management Company 1,176,899 206,387 21.3 747,366 1.4 0.0 09-30-09
Dimensional Fund Advisors, LP 1,161,840 21,000 1.8 -278,265 1.4 0.0 09-30-09
State Street Global Advisors (US) 1,127,675 508,739 82.2 2,445,180 1.4 0.0 09-30-09
CR Intrinsic Investors, L.L.C. 930,000 930,000 100.0 4,854,600 1.1 0.3 09-30-09
MFC Global Investment Management (US), LLC 882,655 99,053 12.6 250,632 1.1 0.0 09-30-09
*Category Headings:
Shs Held - shares held at report date
Shs Chg - position change within reporting period
%Chg - % change
$Chg - market value of the position change
%Out - % of shares outstanding
%Port - % Portfolio
Rpt Date - report date
Page generated 2/9/2010 11:03 PM Eastern Time