Jon Markman

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Posted 4/13/2005


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Pfizer's pain can be your gain

Federal actions have hurt the drug company, but the troubles aren't chronic and the stock's a buy. Pfizer is big, very profitable and likely to stay that way.

By Jon D. Markman

Chronic pain is a way of life for a great many Americans today. Whether its in their backs, joints, heads or extremities, up to 10% of U.S. adults suffer pain that flares up frequently.

A third of all of these chronic sufferers describe their pain as being the worst one can possibly imagine, according to a finding of an advocacy group called the American Pain Society. And the majority of all sufferers have lived with pain that hits them at least six days per week and has done so for at least five years.

It is these people that major pharmaceutical makers Pfizer (PFE, news, msgs) and Merck (MRK, news, msgs) have tried to help by spending billions of dollars in research to develop anti-inflammatory drugs. And it is these people whose lives have been upended by the governments recent jihad against a class of medicines called Cox-2 inhibitors and non-steroidal anti-inflammatories, or NSAIDs. Medicines that go by the prescription names Celebrex, Vioxx and Bextra, or the over-the-counter name Aleve, have given pain sufferers new leases on normal lives.

Down 35% in 5 years
Federal drug bureaucrats approved these drugs at one time, helping Pfizer and Merck put up the sort of revenue and earnings growth that cheered investors. Yet as physicians came to believe that their trust in the clinical studies backing the drugs may have been misplaced and heart-attack concerns emerged to dampen enthusiasm, investors have dumped their one-time heroes. Pfizer shares are off 35% in the past five years, while Merck is off almost 60% since 2001. Both companies have lost a quarter of their value since 2004 alone.
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Does this make any sense, or have investors fears pushed shares down too far?

In my view, the record is clear: Pfizer is one of the greatest companies on the face of the earth. And executives announcement last week that they plan to cut expenses by $4 billion annually through 2008, buy back tens of thousands of shares, boost the dividend and roll out more blockbuster drugs should only have augmented its standing. The stock rallied on the news, but there should be much more to come -- at least 20% over the next year and 100% over the next five. The time to buy is now, perhaps in small doses at first as there could be more downside to come if the broad market slumps, and then more later. No pain, no gain.

After all, lets stand back and get something straight. Pfizer does not make cheeseburgers, sell insurance, hawk discount clothing or manufacture missiles. It does not strip-mine the earth for fossil fuels or pollute the skies, depend on the Internet or create anything that needs to be plugged into a wall. It is not propped up with financial derivatives or off-balance sheet accounting or price-gouging. It is just a powerhouse competitor for the most brilliant but practical scientific ideas generated every day at biotechs, universities and its own facilities, and it does well by doing good. It is not nave or soft-headed to observe, quite simply, that all its 115,000 worldwide employees try to do every day is help people prevent and recover from illness -- and live longer with less pain and discouragement.

Pfizer is one of the good guys
The company may have its faults: Overzealous promotion, overeager pricing or overambitious research. And it may pay its chief executive too much. But at the end of the day, it is pushing the bounds of knowledge in a way that is supposed to be rewarded under the rules of our capitalist system. That is to say: If its effort to peel back the layers of mystery surrounding sickness and the human genome makes it a few bucks, thats supposed to be a good thing. And if it happens to make a whole lot of money in the process, earning an outsized reward for its outsized risk-taking, then mores the better.


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In investing, we are supposed to buy stocks when they are cheap and hated, so long as there is some margin of safety in the purchase. The concept of safety has taken many forms over the years in various situations, but its not really such an obscure concept when it comes to the big U.S. drug makers.

Pfizer has an absolute fortress of a balance sheet -- $7.3 billion in long-term debt compared with $63.8 billion in equity. It generated $16 billion in cash flow last year alone. It could be sued by every lawyer in America, lose the right to market a handful of key drugs and get sued some more. But Pfizer will still live to fight another day because it has the financial resources, emotional smarts and political savvy to battle and win. And because, more importantly, it is probably in the right.

It is a high-grade, ethical research company that does not play shenanigans, said Thomas Kahn, a veteran New York-based value investor who early in his career helped Benjamin Graham with his research. He has also owned Pfizer shares for more than two decades. You do not need to do wrong in America to be sued; you just need to have deep pockets. And if it is somehow forced to pay for some mistakes, it will not do so today or tomorrow, but far down the road. With its balance sheet and earnings power, it could pay $20 billion over years and still not suffer.

Drug makers take risk that benefit all
Would the world not be a much less safe place were it not for the risks taken on by drug makers? Ten years ago, a diagnosis of AIDS was a death sentence. Today, it is more akin to a chronic disease because of the kind of hard-nosed research that big drug firms pursue at great expense. Fortunately, its looking more like Pfizer will not be impeded. The clinical trials that have gotten the company in trouble over its anti-inflammatories may look bad on the surface. Dig down deeper, however, and its hard to see whether the plaintiffs bar will be able to make charges stick. Prescribed dosage levels and individual patient histories will likely prove to be roadblocks to patients trying to pin their heart conditions on Celebrex.

Once the cloud of suits lifts, investors will renew their focus on Pfizers terrific drug portfolio and a dominating sales force of more than 15,000. The company makes 10 drugs with annual sales of more than $1 billion, with the leader being a cholesterol-slashing statin called Lipitor on track to generate $10 billion this year. It also makes Zoloft to assist depression patients and Viagra for sufferers of erectile dysfunction. According to Media General figures, it pulls in 90% and 22% gross and net margins, a return on equity of 17% and return on capital of 15%. In a business where it can take up to a decade to develop a new drug, these are the kinds of results that generate the confidence to try again even as past successes go off-patent. An R&D budget upward of $8 billion says theyll probably figure out the next big puzzles or buy the companies that do.

If you purchase the stock today, it might go down a few bucks. It might even go down another $10, though I doubt it. But over time, Pfizers strength and character will attract risk capital again. And, with the benefit of a decent dividend, buybacks and low price/earnings multiple (Its P/E for 2005 is 13.2), Pfizer will almost certainly reward patient investors with a double by 2011. If they wrote returns like that in marble, the price wouldnt be where it is today, said Kahn.

To buy Pfizer today, in short, you need a strong contrarian bent and the kind of patience that 90% of investors dont seem to be able to muster these days. But as a doctor might say, take a couple of hundred shares and call me in a decade.

Fine print
To learn about the past years worth of Pfizer news, check out the Key Developments page on the MSN Money Web site. To learn more about Pfizer research, visit this page at its Web site. ... The company makes quite a few well-known over-the-counter products, such as Listerine, Rolaids, Desitin, Benadryl, Actifed, Sudafed and Zantac. The company started as a maker of fine chemicals in the mid-1800s, according to its historic timeline. To learn more about Cox-2 inhibitors, visit this page at About.com. Law firms are trying to sign up Celebrex class-action plaintiffs via their Web sites. Click here for an example.

Jon D. Markman is publisher of StockTactics Advisor, an independent weekly investment newsletter, as well as senior strategist and portfolio manager at Pinnacle Investment Advisors. While he cannot provide personalized investment advice or recommendations, he welcomes column critiques and comments at jon.markman@gmail.com; put COMMENT in the subject line. At the time of publication, he held no positions in stocks mentioned in this column.
 

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